| Date | Location | Result | |
| 5/4/2022 | Granville, Ohio | Denison 15, DePauw 10 | Box score |
| 4/27/2022 | Springfield | DePauw 19, Wittenberg 4 | Box score |
| 4/20/2022 | Greencastle, Ind. | Denison 17, DePauw 7 | Box score |
| 04/15/2022 | Gambier, OH | Kenyon College 9, DePauw 8 | Box score |
| Apr 10, 2022 | Delaware, Ohio, USA | DePauw 12, Ohio Wesleyan 6 | Box score |
| 4/6/2022 | Richmond, Ind | DePauw 20, Earlham 1 | Box score |
| 3/31/2022 | Whitiier, Calif. | DePauw 15, Whittier 9 | Box score |
| 3/30/2022 | Redlands, Calif. | DePauw 12, Redlands 11 | Box score |
| 3/28/2022 | Thousand Oaks, CA | DePauw 22, Cal Lutheran 3 | Box score |
| 3/26/2022 | Greencastle, Ind. | DePauw 16, Wooster 5 | Box score |
| 03/13/22 | River Forest, Ill. | DePauw 15, Concordia Chicago 2 | Box score |
| 3/12/2022 | Chicago, Ill. | Univ. of Chicago 22, DePauw 3 | Box score |
| 3/5/2022 | Lexington, Ky. | DePauw 14, Transylvania 11 | Box score |
| 2/26/2022 | Elmhurst, Ill. | DePauw 19, Elmhurst 0 | Box score |
| 2/19/2022 | Greencastle, Ind. | DePauw 11, Carthage 6 | Box score |